Pursuing a career as a Registered Nurse (RN) is a commitment to compassionate care, lifelong learning, and professional excellence. If you're considering this rewarding path in Southern California, you're likely asking a critical question: "What is a typical RN salary in San Diego?" The answer is incredibly encouraging. San Diego stands out as one of the most financially rewarding metropolitan areas for nurses in the United States, with average salaries regularly exceeding $130,000 annually.
This guide provides a data-driven look at what you can expect to earn as an RN in the San Diego area, the key factors that will shape your income, and the robust career outlook for this essential profession.
What Does a Registered Nurse Do?

Before diving into the numbers, it's important to understand the role. Registered Nurses are the backbone of the healthcare system. Their responsibilities are vast and varied, but core duties include:
- Assessing patient health conditions and needs.
- Administering medications and treatments as prescribed by physicians.
- Developing and implementing nursing care plans.
- Operating and monitoring medical equipment.
- Educating patients and their families on managing illnesses or injuries.
- Collaborating with a diverse team of healthcare professionals to provide holistic patient care.
It's a dynamic, challenging, and deeply impactful career that requires a unique blend of scientific knowledge, technical skill, and human empathy.
Average RN Salary in San Diego

San Diego is a top-tier market for nursing professionals. The high demand for skilled healthcare, coupled with a high cost of living, drives salaries well above the national average.
According to the most recent data from the U.S. Bureau of Labor Statistics (BLS) released in May 2023, the average annual salary for Registered Nurses in the San Diego-Carlsbad, CA metropolitan area is $132,120, which translates to an average hourly wage of $63.52.
However, an "average" salary only tells part of the story. The salary range is wide and depends on numerous factors. The BLS data illustrates this spectrum:
- Entry-Level (10th percentile): $95,740 per year
- Median (50th percentile): $132,150 per year
- Senior/Top Earners (90th percentile): $181,190 per year
Data from reputable salary aggregators reinforces these strong figures. As of late 2023 and early 2024:
- Salary.com reports the average base salary for a Registered Nurse (RN) - Staff in San Diego, CA is $124,195, with a typical range falling between $112,242 and $139,328.
- Glassdoor estimates a total pay of $133,595 per year for RNs in the San Diego area, which includes base pay and additional compensation like bonuses or profit sharing.
This data clearly shows that a six-figure salary is not just possible but standard for Registered Nurses in the San Diego market.
Key Factors That Influence Salary

Your specific salary within this range will be determined by a combination of your qualifications, choices, and work environment. Understanding these factors is key to maximizing your earning potential.
### Level of Education
While you can become an RN with either an Associate Degree in Nursing (ADN) or a Bachelor of Science in Nursing (BSN), the BSN is increasingly becoming the industry standard, especially in competitive markets like San Diego. Major hospital systems, particularly those with Magnet designation (a prestigious award for nursing excellence), often require or strongly prefer BSN-prepared nurses. This preference can translate to higher starting salaries and opens doors to leadership, research, and advanced practice roles. Furthermore, nurses with a Master of Science in Nursing (MSN) who work as Clinical Nurse Specialists, Nurse Educators, or Nurse Practitioners will command significantly higher salaries.
### Years of Experience
Experience is one of the most significant drivers of salary growth. Healthcare systems in San Diego typically use a clinical ladder or step-based pay scale that rewards tenure and expertise.
- New Graduate RN (0-1 year): Expect to start at the lower end of the salary range, likely between $95,000 and $110,000.
- Mid-Career RN (5-9 years): With a solid foundation of experience, you can expect to earn at or above the median salary, approaching $130,000-$145,000.
- Senior RN (15+ years): Highly experienced nurses, especially those with specialized certifications and leadership responsibilities, can easily reach the top 10% of earners, commanding salaries well over $160,000.
### Geographic Location
While we're focused on San Diego, it's important to understand *why* it pays so well. San Diego's high cost of living is a primary factor. To attract and retain top talent, employers must offer competitive compensation that allows for a reasonable quality of life. When compared to the national average RN salary of $94,480 (BLS, May 2023), San Diego nurses earn over 40% more, highlighting the immense financial advantage of working in this region.
### Company Type (Work Setting)
Where you work has a direct impact on your paycheck. In San Diego, some of the highest-paying roles are found in large, acute-care hospital systems.
- Large Hospitals and Health Systems: Institutions like UC San Diego Health, Sharp HealthCare, Scripps Health, and Kaiser Permanente are often unionized and offer highly competitive pay scales, excellent benefits, and overtime opportunities. These are typically the highest-paying employers.
- Outpatient and Ambulatory Care Clinics: These settings often provide a better work-life balance with more predictable hours but may offer slightly lower base salaries than high-acuity inpatient hospital roles.
- Home Health and Hospice: This sector offers autonomy and flexibility. Pay can be very competitive, often structured on a per-visit basis, but may come with fewer benefits than a large hospital system.
- Travel Nursing: For nurses with experience, travel nursing contracts in San Diego can offer exceptionally high, short-term pay rates to fill urgent needs. While not a permanent salary, it's a lucrative option that reflects the high demand in the area.
### Area of Specialization
All nursing is demanding, but roles that require advanced training, high-stakes decision-making, and specialized certifications typically come with higher pay. High-demand specialties that often receive pay differentials in San Diego include:
- Critical Care (ICU/CVICU)
- Operating Room (OR) / Perioperative Nursing
- Emergency Department (ED)
- Catheterization Lab (Cath Lab)
- Labor and Delivery (L&D)
Nurses who earn certifications in their specialty, such as the CCRN (Certification for Adult Critical Care Nurses), demonstrate a higher level of expertise and can often negotiate for better pay or qualify for advanced clinical ladder positions.
Job Outlook

The future for Registered Nurses is exceptionally bright. The U.S. Bureau of Labor Statistics projects that employment for RNs will grow by 6 percent from 2022 to 2032, which is faster than the average for all occupations. This growth is driven by an aging population, an increased emphasis on preventive care, and the rising rates of chronic conditions.
In a large, growing metropolitan area like San Diego, this demand is even more pronounced. The combination of a robust job market and a limited supply of nurses ensures long-term career stability and continued salary competitiveness for years to come.
Conclusion

For aspiring or established nursing professionals, San Diego is a premier destination. It offers a dynamic and challenging work environment paired with a compensation package that ranks among the best in the nation. While the average salary of over $130,000 is a powerful incentive, your individual earnings will be a product of your dedication to education, your years of hands-on experience, and the specialized path you choose to follow.
By strategically investing in your skills and seeking opportunities in high-demand settings, you can build a stable, fulfilling, and financially prosperous career as a Registered Nurse in sunny San Diego.