A career as a pediatric oncology nurse is one of the most profound and impactful paths within the healthcare profession. It demands a unique combination of advanced clinical skill, deep empathy, and unwavering resilience. For those drawn to this challenging yet deeply rewarding field, a common and practical question arises: What is the earning potential?
This guide provides a data-driven look at pediatric oncology nurse salaries in the United States. While the emotional and professional rewards are immeasurable, the financial compensation is also significant, with most professionals earning between $78,000 and $118,000 annually, and top earners exceeding $140,000 depending on a variety of key factors.
What Does a Pediatric Oncology Nurse Do?

Before diving into the numbers, it's essential to understand the scope of this specialized role. A pediatric oncology nurse provides comprehensive care to children and adolescents, from infancy to their late teens, who are diagnosed with cancer. Their responsibilities are vast and complex, including:
- Administering chemotherapy, immunotherapy, and other treatments.
- Managing the complex symptoms and side effects of cancer and its therapies.
- Performing blood transfusions and managing central lines.
- Providing vital education and emotional support to patients and their families, helping them navigate a life-altering diagnosis.
- Collaborating with a multidisciplinary team of physicians, surgeons, social workers, and therapists.
This role requires not only a strong foundation in nursing science but also a specialized understanding of childhood cancers, pharmacology, and family-centered care.
Average Pediatric Oncology Nurse Salary

While the U.S. Bureau of Labor Statistics (BLS) groups all Registered Nurses (RNs) together, salary aggregators that analyze specific job titles provide a clearer picture for this specialty.
Based on an analysis of current data, the average salary for a pediatric oncology nurse in the United States is approximately $93,500 per year. However, this is just a midpoint. A more realistic salary spectrum looks like this:
- Entry-Level Range (0-2 years of experience): $75,000 - $85,000
- Mid-Career Range (5-10 years of experience): $90,000 - $110,000
- Senior-Level Range (10+ years, specialized): $115,000 - $140,000+
According to Salary.com, the median salary for a Staff Nurse - RN - Pediatrics is $81,890, but notes that specialized roles like oncology command higher pay. Payscale.com reports a similar average salary of around $89,000 for nurses with pediatric oncology skills, highlighting the significant premium this specialty carries over general nursing roles.
Key Factors That Influence Salary

Your specific salary as a pediatric oncology nurse is not a single number but is influenced by several critical factors. Understanding these can help you maximize your earning potential throughout your career.
### Level of Education and Certification
Your educational foundation is the first major determinant of your salary.
- ADN vs. BSN: While you can become an RN with an Associate Degree in Nursing (ADN), a Bachelor of Science in Nursing (BSN) is increasingly the standard, especially in major hospitals and specialized units like oncology. A BSN often qualifies you for higher-paying positions and leadership roles.
- Master's Degree (MSN): Nurses who pursue a Master of Science in Nursing (MSN) can become Pediatric Oncology Clinical Nurse Specialists (CNS) or Nurse Practitioners (NP). These advanced practice registered nurse (APRN) roles come with greater autonomy and significantly higher salaries, often in the $120,000 to $160,000 range.
- Certification: Obtaining the Certified Pediatric Hematology-Oncology Nurse (CPHON®) credential is a game-changer. This certification, offered by the Oncology Nursing Certification Corporation (ONCC), validates your expertise and commitment to the specialty. Many employers offer a direct salary increase, an annual bonus, or a higher pay grade for certified nurses.
### Years of Experience
Experience is a powerful driver of salary growth in nursing. As you accumulate hands-on experience managing complex patient cases, your value to an employer increases dramatically.
- New Graduates: Nurses new to the field will typically start at the lower end of the salary range as they complete residencies and gain foundational skills.
- Mid-Career Nurses: With 5-9 years of experience, nurses have developed deep clinical judgment and efficiency, often taking on precepting or charge nurse duties, which boosts their earning potential to the national average and above.
- Senior Nurses: Nurses with over a decade of experience, especially those with CPHON® certification, are considered experts. They are prime candidates for the highest-paying clinical roles, as well as positions in education, research, or unit management.
### Geographic Location
Where you work is one of the most significant factors influencing your paycheck. Salaries are adjusted to reflect the local cost of living and regional demand for specialized nurses.
According to the BLS May 2023 data for Registered Nurses, the top-paying states are:
1. California: ($137,690 median annual salary for RNs)
2. Hawaii: ($129,590)
3. Oregon: ($118,600)
4. Washington: ($115,210)
5. Alaska: ($113,440)
Conversely, states in the South and parts of the Midwest tend to offer lower salaries, though the cost of living is also significantly less. A pediatric oncology nurse in a major metropolitan area like San Francisco or New York City will earn substantially more than a counterpart in a smaller city in the Midwest.
### Employer Type
The type of facility you work for also plays a crucial role in compensation.
- Large Academic Medical Centers & Research Hospitals: These institutions (e.g., St. Jude Children's Research Hospital, Dana-Farber/Boston Children's) are often at the forefront of clinical trials and cutting-edge treatments. They typically offer the highest salaries to attract top talent.
- Dedicated Children's Hospitals: Freestanding children's hospitals are major employers of pediatric oncology nurses and offer competitive, market-rate salaries and excellent benefits.
- Outpatient Oncology Clinics: While these settings may offer a more predictable schedule and better work-life balance, salaries can sometimes be slightly lower than in high-acuity inpatient hospital settings.
### Area of Specialization
Within pediatric oncology, there are further sub-specializations that can impact earnings. For example, a nurse specializing in Bone Marrow Transplant (BMT) often commands a higher salary due to the extreme complexity and acuity of the patient population. Similarly, roles in pediatric oncology research or as an infusion nurse may carry a premium due to the specialized skill sets required.
Job Outlook

The future for pediatric oncology nurses is exceptionally bright. The U.S. Bureau of Labor Statistics projects that employment for Registered Nurses overall will grow 6% from 2022 to 2032, which is faster than the average for all occupations.
The demand for highly specialized nurses is expected to be even stronger. As medical treatments for childhood cancer become more complex and an experienced generation of nurses begins to retire, healthcare facilities will have a critical need for skilled and certified pediatric oncology nurses. This high demand ensures robust job security and continued salary growth for professionals in the field.
Conclusion

Choosing a career as a pediatric oncology nurse is a commitment to a life of service, compassion, and continuous learning. While the work is emotionally and mentally demanding, it is also a professionally and financially stable career path.
Key Takeaways:
- Strong Earning Potential: The average salary hovers around $93,500, with a wide range based on controllable factors.
- Education Pays: A BSN is the preferred standard, and an MSN opens the door to top-tier salaries.
- Get Certified: The CPHON® certification is a direct path to higher pay and career advancement.
- Location Matters: Your salary can vary by over 30% depending on the state and city you work in.
- Secure Future: The job outlook is strong, ensuring high demand for your specialized skills for years to come.
For those with the heart and dedication for this vital work, a career as a pediatric oncology nurse offers the rare opportunity to make a profound difference in the lives of children and their families while building a secure and prosperous future.