For registered nurses seeking a career that is both profoundly meaningful and financially rewarding, oncology nursing presents a compelling path. This specialized field places you at the forefront of patient care during one of life’s most challenging journeys. But beyond the immense personal satisfaction, what is the earning potential?
The short answer is that a career as an oncology RN offers a competitive salary that often exceeds that of a general RN, with top earners reaching well over six figures. According to data from Salary.com, the median salary for an Oncology RN in the United States is approximately $86,950, with a typical salary range falling between $77,915 and $97,295 as of late 2023.
This article will provide a comprehensive breakdown of an oncology RN's salary, the key factors that influence it, and the bright future this career holds.
What Does an Oncology RN Do?

An Oncology Registered Nurse (RN) is a highly skilled nursing professional who provides specialized care for patients diagnosed with cancer. Their role is multifaceted and critical to the patient's treatment and well-being. Responsibilities often include:
- Administering Treatments: Safely administering chemotherapy, biotherapy, immunotherapy, and other cancer treatments.
- Symptom Management: Assessing and managing the complex side effects of cancer and its treatments, such as pain, nausea, and fatigue.
- Patient Education: Educating patients and their families about diagnoses, treatment plans, medications, and self-care strategies.
- Emotional Support: Providing compassionate emotional and psychological support to patients and their loved ones.
- Coordination of Care: Collaborating with a multidisciplinary team of oncologists, surgeons, radiation therapists, and social workers to ensure comprehensive patient care.
- Clinical Trials: In some settings, assisting with the management of patients enrolled in clinical research trials.
Average Oncology RN Salary

While salaries can vary significantly, we can establish a strong baseline by looking at data from authoritative sources. Unlike generalist roles, specialized nursing positions like oncology often command a higher base pay due to the advanced knowledge and skills required.
- Salary.com reports the median U.S. salary for an Oncology RN is $86,950, with the top 10% of earners exceeding $105,950.
- Payscale estimates the average base salary for an Oncology Certified Nurse (OCN®) to be around $83,000 per year.
- Glassdoor lists an estimated total pay of $104,850 per year for Oncology RNs in the United States, which includes base pay and additional compensation like bonuses or profit sharing.
It's important to note that the U.S. Bureau of Labor Statistics (BLS) groups all registered nurses together. As of May 2022, the BLS reports the median annual wage for all registered nurses was $81,220. The fact that oncology-specific averages from salary aggregators are consistently higher highlights the specialization's value in the marketplace.
Key Factors That Influence Salary

Your final take-home pay is determined by a combination of factors. Understanding these variables can help you maximize your earning potential throughout your career.
### Level of Education
Your educational foundation is a primary determinant of your starting salary and long-term career trajectory.
- ADN vs. BSN: While an Associate's Degree in Nursing (ADN) is the minimum requirement to become an RN, a Bachelor of Science in Nursing (BSN) is increasingly the standard, especially in major hospitals and cancer centers. A BSN often leads to higher starting salaries and is a prerequisite for leadership roles and advanced certifications.
- Advanced Degrees: Nurses with a Master of Science in Nursing (MSN) or a Doctor of Nursing Practice (DNP) can become Oncology Nurse Practitioners or Clinical Nurse Specialists, roles that come with significantly higher responsibility and salaries, often exceeding $120,000 annually.
- Certification: Obtaining the Oncology Certified Nurse (OCN®) credential is one of the most powerful steps you can take to increase your salary and demonstrate expertise. This certification, offered by the Oncology Nursing Certification Corporation (ONCC), validates your specialized knowledge and can lead to a dedicated salary differential or bonus in many institutions.
### Years of Experience
As with any profession, experience pays. Healthcare employers place a high value on the clinical judgment and refined skills that come with time on the job.
- Entry-Level (0-2 years): A newly licensed RN entering an oncology unit can expect a salary at the lower end of the range, typically from $70,000 to $78,000, depending on location and institution.
- Mid-Career (5-10 years): With several years of experience and potentially an OCN® certification, an oncology nurse can expect to earn closer to the median national average, from $85,000 to $95,000.
- Senior/Lead (15+ years): Highly experienced oncology nurses, especially those in charge nurse, educator, or patient navigator roles, can easily command salaries exceeding $100,000.
### Geographic Location
Where you work is one of the biggest drivers of salary variation. Compensation is often tied to local market demand and cost of living. According to the BLS (May 2022 data for all RNs), the top-paying states offer significantly higher wages:
1. California: $133,340
2. Hawaii: $113,220
3. Oregon: $106,610
4. Washington: $101,670
5. Alaska: $101,640
Conversely, states in the South and Midwest tend to have lower average salaries, but this is often balanced by a lower cost of living.
### Company Type
The type of facility where you work directly impacts your salary and benefits package.
- Major Cancer Centers & University Hospitals: Large, research-focused institutions (e.g., academic medical centers, NCI-Designated Cancer Centers) typically offer the highest salaries to attract top talent for complex cases and clinical trials.
- Community Hospitals: While still offering competitive pay, general community hospitals may have slightly lower salary scales than specialized cancer centers.
- Outpatient Clinics/Infusion Centers: These settings often provide a more predictable, 9-to-5 schedule. Salaries are competitive but may be slightly less than inpatient hospital roles that require night, weekend, and holiday shifts (which come with shift differentials).
- Home Health & Hospice: Nurses providing in-home oncology or palliative care can earn excellent wages, often paid per visit or on a salaried basis.
### Area of Specialization
Even within oncology, further specialization can boost your value. Nurses with expertise in high-acuity areas are in great demand.
- Pediatric Oncology: Caring for children with cancer requires a unique skill set and often commands a higher salary.
- Bone Marrow Transplant (BMT): This is a highly specialized, high-acuity field with rigorous protocols, and nurses with BMT experience are compensated accordingly.
- Radiation Oncology: While distinct from medical oncology, these nurses work closely with radiation treatments and planning.
- Clinical Research Nurse: Nurses who help manage clinical trials for new cancer therapies are vital to advancing medicine and are highly sought after, particularly in academic and pharmaceutical settings.
Job Outlook

The future for oncology nurses is exceptionally bright. The U.S. Bureau of Labor Statistics projects that employment for all registered nurses will grow by 6% from 2022 to 2032, which is faster than the average for all occupations.
This demand is further intensified in oncology due to several factors:
- An Aging Population: As the large baby-boomer generation ages, the incidence of cancer is expected to rise, increasing the need for specialized care.
- Advancements in Treatment: Cancer is increasingly being treated as a chronic disease, requiring long-term management and ongoing nursing care.
- A Growing Number of Survivors: Improved treatments are leading to a larger population of cancer survivors who require follow-up care, surveillance, and management of long-term side effects.
Conclusion

Choosing a career as an oncology RN is a commitment to a challenging, dynamic, and incredibly rewarding field. The financial compensation reflects the high level of skill, knowledge, and compassion required for the role. With a strong median salary and significant room for growth, it is a financially stable and secure career path.
For those looking to maximize their earning potential, the path is clear: pursue a BSN, gain valuable experience, earn your OCN® certification, and consider specializing in a high-demand area of oncology. By investing in your skills and education, you can build a career that not only makes a profound difference in the lives of others but also provides a prosperous future for yourself.